The Carolina Panthers failed to take care of business back in Week 10, during their first matchup with the New Orleans Saints. Despite pulling off one of the biggest upsets of the campaign the Sunday prior in Green Bay, they came up flat against their division rivals—dragging along to a disappointing 17-7 loss.

But can the 7-6 Panthers, who now enter Week 15 atop the NFC South, avoid another letdown to the 3-10 Saints?

Here are the NFL expert picks for Sunday's NFC South matchup from New Orleans . . .

USA Today Sports

Panthers (5): Jarrett Bell, Chris Bumbaca, Nate Davis, Tyler Dragon, Mike Middlehurst-Schwartz

Saints (1): Nick Brinkerhoff

NFL Media

Panthers (9): Daniel Jeremiah, Adam Rank, Marcas Grant, Bucky Brooks, Maurice Jones-Drew, Grant Gordon, Nick Shook, Eric Edholm, Kevin Patra

Saints (1): Colleen Wolfe

ESPN

Panthers (11): Stephania Bell, Matt Bowen, Mike Clay, Jeremy Fowler, Dan Graziano, Kalyn Kahler, Pamela Maldonado, Eric Moody, Jason Reid, Lindsey Thiry, Seth Wickersham

Saints (0):

CBS Sports

Panthers (7): Cody Benjamin, Jared Dubin, Ryan Wilson, John Breech, Tyler Sullivan, Dave Richard, Jamey Eisenberg

Saints (1): Pete Prisco

Pro Football Talk

Panthers (2): Mike Florio, Chris Simms

Saints (0):

Sports Illustrated

Panthers (5): Clare Brennan, Mitch Goldich, Gilberto Manzano, John Pluym, Matt Verderame

Saints (1): Conor Orr

Total

Panthers: 39

Saints: 4

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This article originally appeared on Panthers Wire: Panthers vs. Saints 2025: NFL expert picks for Week 15