Jennifer Aniston is well known for her memorable TV and movie roles — but her high profile relationships have also made headlines throughout the years.

The first of her relationships to hit the tabloids was with fellow actor Tate Donovan. The couple became engaged in 1998 but split soon after.

Following her romance with The O.C. alum, Aniston began dating Brad Pitt after they were set up by their respective agents. Branded a power couple, they were deemed one of the most successful Hollywood marriages at the time. When they split in 2005 after five years, it definitely sparked some controversy as he quickly moved on with his Mr. and Mrs. Smith costar Angelina Jolie.

Justin Theroux, meanwhile, is Aniston’s most recent serious romance. The pair met on the set of Tropic Thunder in 2007 but did not start dating until years later after starring alongside each other in Wanderlust in 2012. They tied the knot in 2015 but announced the end of their relationship two years later.

Scroll down for some of the advice she has shared about love and relationships over the years: